Endocrine Abstracts

Introduction: Diabetes mellitus (DM) is a complex chronic metabolic disease characterized by elevated blood glucose levels due to insulin resistance and the failure of pancreatic beta cells to compensate. T2D and its complications have reached epidemic proportions worldwide over the past four decades [1]. A very rare condition known as Type B Insulin Resistance (TBIR) is characterized by severe insulin resistance and the presence of circulating autoantibodies (autoAb) directed...

Objective: The aim of this study was to investigate sex-specific associations of two established serum selenium biomarkers, i.e. total selenium and selenoprotein P with type 2 diabetes mellitus (T2D) and hypertension in a large cohort of older people.Methods: 1500 participants with available selenium measurements from the Berlin Aging Study II (BASE-II) were included in this study. In the serum samples, spectroscopy was used to quantify total selenium, a...